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Cannabinoids, which are a major constituent of the Cannabis plant, are the subject of extensive scientific and clinical research, and show promise in the management of unmet medical needs. Out of more than 140 cannabinoids, Tetrahydrocannabinol (THC) and Cannabidiol (CBD) are the most extensively studied and more dominant in the plant. THC is a centrally-acting, multi-target neuro and psychoactive molecule that can be extracted from the cannabis plant and used primarily for different clinical indications.
Cannabinoids work through the interaction between cannabinoid 1 and cannabinoid 2 receptors, which are part of the endocannabinoid system (ECS). The endocannabinoid system is a biological system first discovered in the late ’80s and early ‘90s. 95% of the body’s endocannabinoid system is one of the dynamic molecular systems for helping maintain homeostasis. Because of its dynamic role in homeostasis, the ECS is widespread throughout the biological system. In addition to cannabinoids, cannabis plants also express other compounds such terpenes. The potential clinical applications of cannabinoids are ever-expanding.
